Exercise naturally stimulates mitophagy, and research shows that Urolithin A amplifies this effect. A 2023 study found that individuals who combined regular resistance training with Urolithin A supplementation experienced 45% greater improvements in muscle strength compared to exercise alone. The key is creating ‘positive stress’ through workouts, which signals cells to upgrade their mitochondrial quality. Urolithin A then enhances this natural process, leading to superior results. For optimal benefits, aim for 3-4 resistance training sessions weekly, focusing on compound movements that engage multiple muscle groups.