New research shows that Urolithin A’s benefits for muscle health are amplified when combined with adequate protein intake. While Urolithin A improves mitochondrial quality in muscle cells, protein provides the building blocks for muscle protein synthesis. Studies suggest consuming 1.6-2.2g of protein per kg body weight daily, distributed across 3-4 meals, maximizes the synergy. The combination is particularly effective for aging adults looking to maintain muscle mass and strength, with participants showing 28% better muscle retention compared to protein alone.